Honestly... I find that besides certain situations a good Melee Weapon works fine. Just give your crew remodulators. It is annoying how the Borg can be Adapted BEFORE you ever fire a single shot but they never adapt to a good old fashioned butt whoopin' with a blade.

Oh... Nanite Health Moniter is a must...

And one last thing: CRM get it, use it, love it... Borg are so sssslooooooow.