When soloing, it's always advisable to use some self-repair powers if possible (shield repair in particular). Also use Defensive or Balanced presets. Keep re-distributing shield power as much as possible, even before you take damage.
If you find yourself taking a beating too quickly, do 'alpha strikes'. Launch a massive attack (make sure your weapons are fully charged first and all relevant abilities have been activated), then hit Evasive Maneuvers and whatever other escape abilities you have and get the hell out of there ASAP. Rinse and repeat until the job is done.
Lastly, be sure to take down the weakest enemies first. If you can take down weak enemies quickly, then that drastically reduces the amount of enemy fire you have to deal with at any given time. Remember to prioritise enemies that are on the lowest shield/hull rating.
And if all else fails, save the mission for when you are a grade or two stronger.
recommend nuking the worvig first as u dont need to completly kill its hull to remove it from the fight like 30% or something and it has slightly less hull. or u could get a cruiser friend to tnk it for u. no need to do it all solo =)
I went back in time aided the Enterprise to damage the Worvig till is warps away. We both take care of the two D7 BattleCruisers +4. I chase after the Worvig and find it with a single D7 BattleCruiser and both are +4. Again I damage the Worvig enough for it to cloak and make a run for it then I destroy the BattleCruiser. I go looking for the Worvig which is supposed to be too damaged to get very far or stay cloaked to find it fully healed along side another BattleCruiser +4 and this time both are like 10x's stronger, 10x's more powerful fire power, and 2x's faster. In the earlier battle I managed to get the Worvig to about 30% and destroy the other BattleCruiser without being destroyed though I was about 75% hull. As I searched for the Worvig I healed to 100% just before I came within firing range. So its not like the Worvig had tons of time to do repairs yet it was at 100% and this last battle I can't even do any damage to either ship before being destroy. I tried applying all buffs right as battle began ... throwing everything at it but I can only shoot in one direction with my phaser and quantum torpedo... so I purchase a photon mine launcher and will go back and see how that helps.
Solo'd through it since tihs time around the enemies were only +3. It was tough though. Each battle left me sitting there waiting while my crew repaired my Cruiser. All I can say is you have to utilize everything you have and hopefully you've chosen the right BO skills. I am still used to the attributes my BO's had in beta but I think those were incorrect since I can't find those same skills for them as Ensigns only as Lt.'s.