Seriously crash on every indoor away mission, making it impossible to complete them.
Yup yup. Big nasty crashes on a 5870/Q6600 system. Pretty much happens each time I activate any kind of ability that involves particle effects or the like. The dumps that it generates are also pretty impressive in size.
I also tend to crash a lot in the indoor ground missions. It only really happens when I get into combat, and I dunno if it's just my imagination or not but it also seems at its worst in cramped areas like narrow corridors.
Oddly enough the outdoor missions seem to work pretty well for me.