- Jean-Luc Picard, exhausted but defiant, shouting at Gul Madred before returning to the Enterprise
2. In The Pale Moonlight: DS9
"That's why you came to me, isn't it captain? Because you knew I could do those things that you weren't capable of doing. Well, it worked. And you'll get what you wanted: a war between the Romulans and the Dominion. And if your conscience is bothering you, you should soothe it with the knowledge that you may have just saved the entire Alpha Quadrant, and all it cost was the life of one Romulan senator, one criminal... and the self-respect of one Starfleet officer. I don't know about you, but I'd call that a bargain."
"So... I lied. I cheated. I bribed men to cover the crimes of other men. I am an accessory to murder. But the most damning thing of all... I think I can live with it. And if I had to do it all over again, I would. Garak was right about one thing, a guilty conscience is a small price to pay for the safety of the Alpha Quadrant. So I will learn to live with it. Because I can live with it. I can live with it... Computer, erase that entire personal log."
Two of the best bits of dialogue of any Star Trek show in any of the series'.
Definitely the scene in TNG when Dr. Crusher and Cpt. Picard meet in the doorway between the bridge and the conference room. Beverly and Picard could barely keep their hands off each other. It was a fantastic! Would have been SOOOO awkward afterwards...
Quarlo beat me to it, the ending monologue from In The Pale Moonlight. That and Sisko's bombing of a Maquis settlement cemented him as my favorite captain. Because kids, sometimes the ends really do justify the means.