Give the CRM to a trustworthy boff. It's an amazing expose weapon easily one of if not the best in the game, and generally it's a good idea to pack your boffs with expose weapons because they make awful use of exploit weapons and stick to the exploiting yourself. You can always take it away from them if you want it for an STF or other group mission.
Melee does pretty well against shieldless Borg and non-elite tactical drones. Their tactics tend towards the Zombie Apocalypse Shuffle, and they like to cluster around. Melee has one of the best AoE knockbacks in the game and can make those crowds a lot more manageable, with effective science support.