Keeping very tight control on the BOFFs usually makes it manageable. (The last time I only lost one BOFF).
However, sometimes, one of the BOFFs lost is the one advancing the dialogue, which is *very* odd.. "Um.. didn't you die in the lava? Who's talking to me? It's a ghost!" It does make the Fire Caves seem like one of those many "It's just a dream" episodes of DS9/Voyager though.