Funnily enough, I think one of the best ways to play STO is on a 1080p tv, but setting the game to run at 1280x720 and letting my TV upscale it. I can turn on all our higher settings and it still runs smooth. This is basically how some devs get their console games looking so good on 5 year old hardware like the 360: render fewer pixels but make em as pretty as possible.
haha, Thats what i do, play STO on a 40" 1080p tv, but with the full res and everything maxed.
Modern hardware is sooo nice