Asus Striker II Extreme
Intel QX9770 Extreme Edition
8 GB RAM
2x EVGA GTX 280 using 290.53 driver
Windows 7 x64
I've troubleshot this by removing and replacing cards. I can get to the main menu until I enable SLI, then when launching the game, it locks up at loading. Cannot ctrl-alt-del out computer stops responding. Sometimes it will go to the character creation screen and flash intermittently before locking up... Disabling SLI makes it work like a champ, so I've set a program specific exclusion in the Nvidia control panel and it works fine...