The Janeway Maneuver: "There's coffee in that nebula." *proceeds to harvest 'coffee' from a living space creature and fires phasers and photons at it.* - all in a days work.
The sad thing about this is... there are actually nebulas out there composed of the alcohol we drink. If we could filter out all the toxic stuff from it, there would be so much beer made from it that breweries would go out of business...
SubNuc, Viral Matrix, Tractor Beam, Tyken's Rift, & Target shields while flying head-on at target. When passing by hit Photonic Shockwave or Feedback Pulse, Target Engines, & finish with a rear-mounted Tricobalt or Harg'Peng. It helps to have Polaron Weapons & maxxed Flow Capacitors for this.
The Arcen Maneuver:
Activate the Ablative Generators, then Ramming Speed. Aim for closest target.
***use at your own risk***
I like my Sci guy & I like my Sci ship & that's that.