Like everything else, DOFFing gets boring after doing it for a long time. And really boring if you're doing it on a whole bunch of characters.
With this change, it will be boring no longer. It will become an entirely ignored portion of the game.
Acquiring and donating items for Starbase construction feels to many people like a waste of time and effort.
With this change, it will feel like a waste of time and effort to very nearly EVERYONE.
Now this all assumes they don't add some other way of getting DOFFs much cheaper AND a way to get rid of DOFFs you don't want and get something out of it. But let's be honest, I don't see that happening.
This looks like nothing other than a MASSIVE penalty. If their intent is to increase sales of c-store DOFF packs, I'm sure it will be successful...for a while. And then those c-store DOFF packs will entirely stop selling as nearly everyone that plays STO because they enjoy DOFFing will move on to a different game.