If science abilities could miss, they'd need *much* shorter cooldowns.
With the way the game is currently balanced, if you need something like SNB to kill someone, there really isn't an alternative, so if it missed you are just screwed.
It definitely woudn't be something to introduce all by itself...lol, not by a long shot.
It's complicated by the nature of the various abilities out there.
Is FoMM actually a debuff to the target or is it a buff to everybody firing at that target? Is it a target painter or is it some networked buff to all the friendly targeting systems? Depending on how it actually works - physical mark on the target or buff to friendly systems... it might miss or it might never miss.
Tachyon Beam on the other hand - well, it's obviously a beam. It's even a beam that can be broken by breaking the arc. So if it can miss after it hits, why couldn't it miss before it hits?
There are a lot of abilities out there where such a change wouldn't change anything - others that it would...
...but none of it should be considered in the least without looking at how it would affect everything.
That SNB is needed to kill something...well, that's not a good thing in of itself, eh? I still don't think that SNB should strip all buffs - much like I don't think a cleanse should be a complete cleanse.
Everything's to the extremes... it's Star Yo-Yo's In Space...meh.
Remember, things were sorta balanced at the start of all this. On turn rate and arcs. This was all done, and done well. It was broken slowly, as the skill tree changed, as captains came out of thier class ships with wonderous abilities intact, etc. It's been a slow process, but the trail is there to follow.
So keep in mind much has changed. And even if you gave TB a fifty percent chance to miss, would I use it? Sure I would. It means half the time I'd STILL have a sure kill. That is WAY better odds than shooting at a high defense ship isn't it? And, please, don't think I'm saying THATS the way to play. I'm pointing out that its there, and .........if it's there it creeps into everything. Even if your not INTENTIONALLY trying to exploit it.
Like DHC's. Why the hell are they so crazy. Please refer to acc/def/crit and the primer on H and D. It's almost IMPOSSIBLE to make DHC's look crappy at this point.
So sure, some things could bear a looking at, but I'd wait till AFTER the potential to bury someone in a defense deficit was eliminated. Once that is gone, you may have different views on Sci abilities than you do now and that would be understandable.