I seem to be doing pretty well with targeting in space combat, but I do have one issue.
I have my options set so that as soon as I kill one target, I hit Fire All Beams and the next target is selected automatically as long as it is in range. But this doesn't always work. I'd say about one out of five times I have to manually select a target. This is especially apparent when I'm taking on a wing of fighters.
If there is a 'Space Combat Targeting Primer', feel free to link me to it!