If you use prototype jevonite hardpoints, those can boost your SIF by 100 skill points, which can mean around 25k hull on most cruisers, so I would imagine that using those in conjunction with a deflector that also boosts these points such as the MACO deflector could do it, though I've not tested it.
The adapted MACO shield has some of the highest in the game, combined with Mk12 VR Field Generators could boost your shield HP by a lot as well assuming that you had maximum points in shield systems, the additional gain from the romulan passives and or a deflector that boosted it.
Again I have no evidence to prove this would work, but at least on paper it sounds possible.
They who can give up essential liberty to obtain a little temporary safety, deserve neither liberty nor safety. - Benjamin Franklin