I'm now more scared of these guys than I am of the crystalline entity. Not human freighters... not the ferrengi at the starbase... only wandering Ferrengi Freighters, and then only if I attempt to trade with them. CTD, CTD, and a lock-up this time where I had to force-close the game client.
Ok! I've learned my lesson! Never trade with a Ferrengi!
Intel Quad Core, WinXP, Nvidia 8800GT. No crashes with any other situation yet. Just the Ferrengi Freighters.