I have an nVIDIA GeForce 6150SE nForce 430. The game was running great until the last patch. As soon as i start the game, it makes 'trash' all over my screen and i can't see the game as it's all distorted. When i exit the game, the 'trash' remains on my screen and i have to reboot to fix it.
This only happens when i run STO. Works fine in any other game.
If you haven't recently updated your graphics drivers, you should try that. If you did just recently update your drivers, and then the problem started, you should try rolling back to a more stable version.
If it looks like you are still having the problem, please submit a support ticket with your full system specs and an engineer in customer service will have a look at it for ya.