Spec in AoE abiltiies (specifically, AoE Kinetic Damage, AoE Confuses)
Single Target Ability Debuffs help too.
If a escort:
spec in shield takedowns and everything to maximize burst damage
here's my favorite one that helps a team overcome carrier more easily:
Originally Posted by Darren_Kitlor
A Happy, Happy Fun Build Against Carriers:
Nebula Science Vessel
On your LtCmdr. Engineer Boff have at least:
Eject Warp Plasma
Emergency Power to Aux
On your Cmdr. Science Boff have:
Tachyon Detection Grid
Spec your skills to maximize these eight abilities at least. Aux to Inertial Dampeners can also help with turning your ship to get a proper facing.
Make sure everyone approaches the carrier from different angles.
Fire the Tachyon Grid on approach (to decloak support craft)
Fire TSSS on the Carrier, just in case you get lucky and can take them down.
When shields are starting to weaken, fire gravity well and viral matrix.
Scramble Sensors to have all those trash fighters cannibalize the carrier mama-bird
When that fades, fire boarding party (crew levels should be at a point to interrupt powers)
Once aboard, fire Eject Warp Plasma
As fighters are launched, scramble sensors is a blessing. Scrambled fighters will devour their parent craft. Having escorts hang back and wait for the decloak is preferable to some escort thinking he's the biggest cowboy this side of the Rio Grande.
AoE abilities like Eject Warp Plasma and Gravity Well can crush fighters too - just make sure you're firing them close enough to the carrier. For added hilarity, use target engine subsystems on the carrier while other science vessels fire off their anomalies.