(no, I'm not under the delusion that this is a cruiser But the arrays offer good flexibility during "evasive maneuvers", with the cannons and torps for punch. (and yes, I have Fire At Will and both Spread and High Yield.) I'm considering swapping out the front array for another set of cannons, though, leaving just the ones in back. )
Please don't do STFs with this build, you have less than half the DPS of a properly geared escort.
You can yes, and it will be effective, a lot less effective than DHCs though, because of power drain cycles.
I have found on my Defiant build that in PvE (and STFs are still PvE) that having DCs instead of DHCs is a bit better since they have a chance to proc 2x as much. So if you are using Phasers, Tetryons or Disruptors, things go boom a bit faster. However, with each shot the target's defense is counted twice compared to DHCs, which is why I don't recommend it for PvP. But it does a nice job in PvE.
OP If you like your Tetryons, use them, the way weapons work in PvE it makes no real difference. Pick the weapon you want the proc for. Or how it looks...