New Romulus does not have the same services as ESD or DS9. And with the reputation system, people will be wanting to buy hypos, major regenerators, shield charges, etc. As far as I know, there is no vendor that sells them on New Romulus. Not even the Tuffli freighter has a hypo vendor. So really, New Romulus can't function as a base of operations. That will always still be ESD or DS9. And you can't transwarp there either. The best you can do, is transwarp to fleet base, and then transwarp to Pi Canis assuming you have unlocked it.
Come join the 44th Fleet.
Maybe that is a big problem with New Romulus as a place to go - NOTHING THERE!
No, its just its not meant to function as a base, Bajor have similar issues since you dont have contacts for Contraband, Shipyard or the STF essentials.
Also DS9 is a Transwarp location, when I was running STFs I was based in DS9 since if my ship was injured I could repair it, if my character was injured I could remove it ... only ESD offers the same but its 10 times more annoying to navigate and still lacks a Dabo table.