If i remember correctly,the game is now set in the 25th century.
I would like to see it possible, for scientist researchers to come up with new anti-borg ground and space weapons.
Ground weapons that do not need re-modulating.
Space weapons,both Torpedo and energy weapons that can easily take out and borg ship including the borg cube.
U.S.S Voyager under captain janeway easily took out a borg cube,using transphasic torpedoes. end game was the voyager episode.