I don't really want nerfs, but I'd like to see various abilities fixed, and it'd be nice to see engineering and science captains (and the corresponding ships) given more of a role in PvE, with their abilities adjusted so they can actually compete again.
Currently it's all about damage, which means it's a tactical captain + an escort for pretty much everything these days, because there's nothing that needs a tank (or rather, no high level NPCs that a tank can withstand any better than a decent escort in practice). Tactical abilities seem to spill over onto science ones, meaning tactical captains are better science captains than science captains, and many tactical abilities combine the effects of a bunch of engineering and science abilities into a single ability. Ship manoeuvres seem to be the worst of these, though I'm not sure I'd want them nerfed in terms of their current positive effects, but it might be good to see them have some disadvantages to balance their use, so that some manoeuvres make you a glass cannon, while others let you take some heat off but reduce your own damage for a while.
Yeah, nerf everybody! Especially those darned tac captains. I'm sick and tired of making it through ESTF's with the optional in 10 minutes. Damned those escorts! I'm raking in the dilithium way too fast. This has to stop!