If you have purchased a Legacy or Starter Pack, please see this thread for instructions on how to claim your items in-game. (Please see the yellow text in the linked thread for instructions on creating a Reman.) (Not seeing your pack in-game? Please see the lime-green text in the linked thread above for information.)
If you have additional questions about the Legacy or Starter pack, please read this FAQ.
Thanks SO MUCH for all your support, and we'll see you in-game!
Short answer. If you've got enough hard drive space, copy the contents of the DVD to your hard drive, run from there, profit.
I didn't have that much space, so I copied the setup.exe, and ran it, causing it to at least make the appropriate directories under Program Files. Then, I copied the piggs folder from the DVD to the "proper" place on the hard drive.
When it was done, I ran the patcher, which installed/mirrored al the files that were missing.
Believe it or not, my creaky P4 2.8ghz with 6800GT will run STO at the lowest settings, but I was still able to bump up the res from 1024x768 to 1280x1024.