Last night I encountered an odd issue where I found some loot but couldn't pick it up.
The only other issues I noticed were minor like an NPC dialog graphic and a mission reset (resolved by "aborting" the mission).
wonder if dxdiag might provide any clues as to the crashes mentioned
the problem been happening since they added that section of the game. though lately it been happen less it is still anoying as you have to do a file verify after the crash. If you skip the verify it is likely the game will crash on login.