I purchased a brand new video card today.
Nvidia GTX 295
Latest Geforce drivers
With the Nvidia Physx feature enabled, my graphics drivers crash every few minutes when playing StarTrek online. This issue only occurs when playing StarTrek Online.
Other games and demo applications which use the Physx acceleration do not experience this issue.
Since the issue only occurs with StarTrek online, stops whee Physx acceleration is disabled. This leads me to conclude your game is doing something very strange with Physx acceleration. I notice that in the StarTrek online home folder there are several files related to Physx acceleration. I am not sure what your using this for in game, but I believe there is a serious issue with your code related to this function.
Please let me know if you need any further information for this bug.