Graphfics Card: EVGA Nvidia Geforce 9800 (I have SSC but they are really hard to go so get the GTX). THe 200 nvidia seres are going down in price pretty quickly and just one will run fast, quite, and cool. Good luck shopping around.
THe rest of my setup is below. Game runs awesome on 1920x1200 max settings 120hz refresh hdmi hookup.
EVGA Motherboard 780i SLI
Intel 3.16 Core Duo
1333 front side bus
Windows Vista 64 bit Home Premium
8 gigs ram (only need 4) - fastest ddr 2 ram with 1333 front side bus spec