Port forwarding is for incoming connections to your PC. As far as I know STO doesn't making any outgoing connections to your PC so port forwarding would be moot.
Port forwarding is not a performance thing, it's a "forward this port that my from my router to my PC so my PC can handle the incoming conenction" thing.
Every time you access a website, etc a different port is used on your PC, you don't forward all those because you don't need to, you're making an outgoing connection (usually port 80 for websites btw).
But for incoming connections, if you wanted to run a webserver on the standard 80 port you'd need to forward 80 to your PC. Although the remote client connecting to your PC would be using a port between 1025 and 65535.
Not to mention that 443 is the standard port for HTTPS connections to secure web servers (80 is used for HTTP).
No game would ever need that open, and most users wouldn't need to forward it, unless they were running a web server with HTTPS content. Opening ports willy nilly is just a bad idea. Don't do it. If STO needed them open, I'm sure there would be a help page explaining it.
Irrelevant... maybe... but those are ports that the Nettest tool you provide opens and tests your connection to Cryptic. If my information is wrong... you gave it to me.
(I might be wrong here but this is how I understand it: )
I think you're misunderstanding nettest. One of the things it tests for is - "is the user's ISP traffic shaping STO traffic?". Port 443 is tested as a baseline because it's hardly ever touched by ISPs traffic shaping (it's used for https://). STO doesn't use that port itself for game communication - nettest shows a comparison against that and the ports STO actually uses (in the 7k range) so you can see if 443 gets through fine while the 7k ports get massively shaped.
But, it's a moot point anyway, you don't need to forward ports for STO. Port forwarding is needed when an external body is trying to initiate a connection on a specific port to your machine through your router. All STO communication is initiated client side. All connections are opened from your computer and connect to the server (as opposed to opened from the server to your computer) - as such there's no port forwarding needed.
EDIT: The only time you'd need opened ports is if you were somewhere like a university network and they were blocking all outbound traffic on the 7k ports by default.