The game takes place in the original timeline, after the new movie. - Romulas is destroyed, but vulcan is still there. Spock went through the hole, and life goes on without 'em. I don't even think there is a comissioned enterprise anymore.
Or to think of it in easier terms, the only thing that has really happened, from the movie, was the supernova destroying Romulas and spock used the red matter to stop the supernova then he fell into the hole. We are not living in the "black hole" alternate timeline, but the original.
After that, the various powers are gearing up for territorial war.
I don't even think there is a comissioned enterprise anymore..
the current enterprise is ether the prototype 3 necel galaxy class or a refitted sovrigne class thats captaned by a captain Data (thanks to mr le forge and the instertute that b3 was sent too they were able to re-creat data)
Picard was working with ambassador spok before the romulas incident and has since gone missing and riker is still captaning the titan in deep space.
if you look around the STO website you will find timeline stories that explaines it all
no one really brings it, up but the writters of Star trek (2009) wrote a nice tie in comic that takes place before the movie that goes into detail about data being the captain and spock and nero. this game uses alot of the story elements brought up in that comic, or at the very least, they worked together. for instance, Data and his crew wear uniforms from this game (Starfleet B01).
the comic is called Star Trek: countdown its very well written and get into alot of this stuff